ISSN 0869-6632 (Print)
ISSN 2542-1905 (Online)

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Postnov D. D., Sosnovtseva O. V., Postnov D. E. Autonomous and nonautonomous dynamics of functional model of serotonergic neuron. Izvestiya VUZ. Applied Nonlinear Dynamics, 2011, vol. 19, iss. 3, pp. 26-44. DOI: 10.18500/0869-6632-2011-19-3-26-44

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Russian
Heading: 
Nonlinear Dynamics and Neuroscience
Article type: 
Article
UDC: 
577.31
DOI: 
10.18500/0869-6632-2011-19-3-26-44

Autonomous and nonautonomous dynamics of functional model of serotonergic neuron

Autors: 
Postnov Dmitrij Dmitrievich, Saratov State University
Sosnovtseva Olga Vladimirovna, Danmarks Tekniske Universitet
Postnov Dmitry E, Saratov State University
Abstract: 

Serotonin is a key modulator of neuronal activity both at the system level and at the level of local (short-range) interactions. However, in contrast to the synaptically connected neuron ensembles, there are much less qualitative models that describe the serotonin-controlled neural circuits. In this paper, we propose a relatively simple model of serotonergic (serotonin-releasing and serotonin-sensitive) neuron. It is shown that specific features of both autonomous and nonautonomous dynamics of such model are considerably dependent on a weak depolarizing voltage-independent current of neuron and on the presence of serotonin auto-receptors. Our work is aimed on development of «computational image» for basic serotonin-controlled neural circuits, which role for basic neuronal features plays the famous FitzHugh–Nagumo model. 

Key words: 
Serotonergic neuron
functional model
weak depolarizing current
bursting pattern
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Received: 
09.12.2010
Accepted: 
09.12.2010
Published: 
29.07.2011
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