ISSN 0869-6632 (Online)
ISSN 2542-1905 (Print)

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Postnov D. D., Sosnovceva O. V., Postnov D. E. Autonomous and nonautonomous dynamics of functional model of serotonergic neuron. Izvestiya VUZ, 2011, vol. 19, iss. 3, pp. 26-44. DOI:


Autonomous and nonautonomous dynamics of functional model of serotonergic neuron

Postnov Dmitrij Dmitrievich, Saratov State University
Sosnovceva Olga Vladimirovna, Danmarks Tekniske Universitet
Postnov Dmitrij Engelevich, Saratov State University

Serotonin is a key modulator of neuronal activity both at the system level and at the level of local (short­range) interactions. However, in contrast to the synaptically connected neuron ensembles, there are much less qualitative models that describe the serotonin­controlled neural circuits. In this paper, we propose a relatively simple model of serotonergic (serotonin­releasing and serotonin­sensitive) neuron. It is shown that specific features of both autonomous and nonautonomous dynamics of such model are considerably dependent on a weak depolarizing voltage­independent current of neuron and on the presence of serotonin auto­receptors. Our work is aimed on development of «computational image» for basic serotonin­controlled neural circuits, which role for basic neuronal features plays the famous FitzHugh–Nagumo model.

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