ISSN 0869-6632 (Print)
ISSN 2542-1905 (Online)


For citation:

Klimova O. A., Semenova M. A., Anishchenko T. G., Igosheva N. B. Normalized entropy in the evaluation of cardiovascular responses to different perturbations in male and female rats. Izvestiya VUZ. Applied Nonlinear Dynamics, 2003, vol. 11, iss. 2, pp. 108-115. DOI: 10.18500/0869-6632-2003-11-2-108-115

This is an open access article distributed under the terms of Creative Commons Attribution 4.0 International License (CC-BY 4.0).
Full text PDF(Ru):
Language: 
Russian
Article type: 
Article
UDC: 
577.3+517

Normalized entropy in the evaluation of cardiovascular responses to different perturbations in male and female rats

Autors: 
Klimova Oksana Anatolevna, Saratov State University
Semenova Maria Alekseevna, Saratov State University
Anishchenko Tatyana Grigorievna, Saratov State University
Igosheva Natalia Borisovna, Cambridge Clinical Trials Unit
Abstract: 

In this research we studied the cardiovascular sensitivity to parasympathetic blockade in normal and castrated male and female rats under usual and stress conditions using the traditional physiological measures and a new measure of complexity of blood pressure dynamics - normalized entropy Е/Н. The results showed that changes in E/H were more pronounced and prolonged in comparison with heart rate and blood pressure. Also, unlike the latter, Е/Н increased in one part оf rats аn decreased in another part оf ones. These quantitative аnd qualitative particularities in Е/Н changes give evidence that using a new measure of complexity degree of blood pressure signal one can receive an additional information about the changes in cardiovascular system evoked by different perturbations.

Key words: 
Acknowledgments: 
The research was partially supported by CRDF(REC-006) grant and Russian Ministry of Education grant RD 02-1.4-261.
Reference: 
  1. Matyushin AI. The protective role of estradiol in extreme conditions. Bulletin of Experimental Biology and Medicine. 1992;114(11):497–500 (in Russian).
  2. Igosheva NB, Pavlov AN, Anishchenko TG. Methods for Analyzing Heart Rate. Saratov: «College»; 2001. 120 p. (in Russian)
  3. Anishchenko TG, Yanson NB, Pavlov AN. Can the heart function be regular? J. Commun. Technol. Electron. 1996;42(8):1005–1010 (in Russian).
  4. Pavlov AN, Yanson HB, Anishchenko VS, Gridnev VI, Dovgalevsky PY. Diagnosis of cardiovascular pathology by calculating the highest Lyapunov exponent using a sequence of QC intervals. Izvestiya VUZ. Applied Nonlinear Dynamics. 1998;6(2):3–14 (in Russian).
  5. Anishchenko VS, Saparin PI, Safonova MF. Measuring and computing complex for diagnosing complex modes of self-oscillations. J. Commun. Technol. Electron. 1992;37(3):467–478 (in Russian).
  6. Anishchenko TG, Igosheva NB, Khokhlova HE. Normalized entropy in assessing the characteristics of the cardiovascular system’s reactions to stressors in individuals of different sexes. Izvestiya VUZ. Applied Nonlinear Dynamics. 1997;5(1):81–92 (in Russian).
Received: 
31.01.2003
Accepted: 
15.04.2003
Available online: 
16.11.2023
Published: 
30.05.2003