ISSN 0869-6632 (Print)
ISSN 2542-1905 (Online)

response differentiation

Feature of simultaneous influence of excitatory synaptic currents on a neuron with differential responses

The simultaneous influence of excitatory synaptic stimuli (the tonic AMPA and NMDA currents) on the neuron model with response differentiation is studied. It is shown that different types of neuron activity (rest state, low frequency or high frequency firing) are observed depending on the conductance of the AMPA and NMDA receptors. It is found that for the certain parameters values if both types of receptors are activated simultaneously, it is possible to obtain maximal frequency to be approximately 20% greater than that with the NMDA current alone.