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Meglinsky I. V., Boas D. A., Yodh A. G., Chance B., Tuchin V. V. Development of correlation of laser eradiation intensity fluctuations techniques for non-invasive monitoring and measuring of blood flow changes. Izvestiya VUZ. Applied Nonlinear Dynamics, 1996, vol. 4, iss. 6, pp. 72-81.

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Russian
Heading: 
Applied Problems of Nonlinear Oscillation and Wave Theory
Article type: 
Article
UDC: 
535.36

Development of correlation of laser eradiation intensity fluctuations techniques for non-invasive monitoring and measuring of blood flow changes

Autors: 
Meglinsky Igor Vladislavovich, Saratov State University
Boas David Alan, Tufts University
Yodh Arjen G., Pennsylvania State University
Chance Britton, Pennsylvania State University
Tuchin Valerij Viktorovich, Saratov State University
Abstract: 

We have non-invasively measured in vivo blood flow changes using photon correlation spectroscopy (Diffusing Wave Correlation Techniques) with а simple correlation diffusion model to study and quantify blood flow in the human arm during cuff ischemia. The method utilizes the Doppler broadening of light that arises in a multiply scattering dynamic media, and is also responsive to changes in absorption and scattering coefficients. Our measurements clearly show blood flow changes with cuff pressures, including the hyperemic overshoot after cuff release, that qualitatively agree with the physiological behavior of the cardiovascular system. In this article, we present method, results and discuss the clinical relevance of our findings.

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Received: 
04.09.1996
Accepted: 
30.12.1996
Published: 
08.04.1997
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