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Bednov A. A., Uljanov S. S., Tuchin V. V., Brill G. E., Zakcharova E. I. Investigation of lymph flow dynamics using speckle-interferometry. Izvestiya VUZ. Applied Nonlinear Dynamics, 1996, vol. 4, iss. 3, pp. 42-52.

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Language: 
Russian
Heading: 
Applied Problems of Nonlinear Oscillation and Wave Theory
Article type: 
Article
UDC: 
535.39.01

Investigation of lymph flow dynamics using speckle-interferometry

Autors: 
Bednov Andrei Aleksandrovich, Saratov State University
Uljanov Sergej Sergeevich, Saratov State University
Tuchin Valerij Viktorovich, Saratov State University
Brill Grigorii Efimovich, Saratov State Medical University named after V. I. Razumovsky
Zakcharova Ekaterina Ivanovna, Saratov State Medical University named after V. I. Razumovsky
Abstract: 

For some human diseases both the blood and lymph microcirculation parameters are changed. They contain a useful diagnostic information. Unlike a blood flow, a lymph motion is more various and complicated in the microcirculatory system. Lymph flow in microvessels is non-stationary and randomly changed in time. By now the existed methods of determination of motion parameters of these flows have not completely developed. They are, in most, of qualitative character. 
In this paper е blood and Iymph motion has been considered from е viewpoint of non-linear dynamics. Speckle-interferometric method of investigation of dynamic characteristics of biofluids has been proposed. The method has been applied for investigation of blood and lymph flows ш microvessels. Using the method of focused Gaussian beam diffraction there were defined the values of V, characterizing the mean temporal value both of blood and lymph flow velocity and Sum v, а value indicating the deviation degree of spectral envelope from а Gaussian curve. The parameter Sum v demonstrates the velocity range presenting in the flow and, besides that, gives an information about spatial-temporal velocity changes in registered region. 
The research of lymph flow dynamics has been carried out under the influence of lymphotropic factor. It has been shown that lymph microvessels can act in different states at which the structure of lymph flow and its temporal dynamics are changed qualitatively.

Key words: 
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Received: 
05.03.1996
Accepted: 
17.05.1996
Published: 
15.12.1996
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