ISSN 0869-6632 (Print)
ISSN 2542-1905 (Online)

For citation:

Bogatyrev V. A. Laboratory diagnostic system of toxicity of nanomaterials. Izvestiya VUZ. Applied Nonlinear Dynamics, 2014, vol. 22, iss. 6, pp. 3-14. DOI: 10.18500/0869-6632-2014-22-6-3-14

This is an open access article distributed under the terms of Creative Commons Attribution 4.0 International License (CC-BY 4.0).
Full text PDF(Ru):
(downloads: 259)
Article type: 

Laboratory diagnostic system of toxicity of nanomaterials

Bogatyrev Vladimir Aleksandrovich, Russian Academy of Sciences' Institute of Biochemistry and Physiology of Plants and Microorganisms

The paper describes the results of experimental work of students and post­graduate students of the Department of Biophysics of the FNP SSU and the laboratory of nanobio­technology IBPPM RAS to identify the potential danger of plasmon­resonance nanomaterials in biomedical research, namely the development of software and instrument complex spectrophotometric and microscopic measurements to estimate viability of microalgae Dunaliella salina and determine the toxicity of the components of incubation medium.

  1. Dykman LA, Bogatyrev VA, Shchyogolev SY, Khlebtsov NG. Gold Nanoparticles: Synthesis, Properties, Biomedical Application. Moscow: Nauka; 2008. 319 p. (in Russian).
  2. Khlebtsov N, Bogatyrev V, Dykman L, Khlebtsov B, Staroverov S, Shirokov A, Matora L, Khanadeev V, Pylaev T, Tsyganova N, Terentyuk G. Analytical and theranostic applications of gold nanoparticles and multifunctional nanocomposites. Theranostics. 2013;3(33):167-180. DOI: 10.7150/thno.5716.
  3. Available from:
  4. Bogatyrev VA. Colloidal gold in light microscopy. Izvestiya VUZ. Applied Nonlinear Dynamics. 2012;20(1):43-48 (in Russian). DOI: 10.18500/0869-6632-2012-20-1-43-48.
  5. Masyuk NP, Posudin YI, Lilitskaya GG. Photomovement of the Cells Dunaliella Teod. (Dunaliellales, Chlorophyceae, Viridiplantae). Kiev; 2007. 264 p. (in Russian).
  6. Mecozzi M, Onorati F, Oteri F, Sarni A. Characterisation of a bioassay using the marine alga Dunaliella tertiolecta associated with spectroscopic (visible and infrared) detection. International Journal of Environment and Pollution. 2008;32(1):104-120. DOI: 10.1504/IJEP.2008.016902.
  7. Available from:
  8. Hazani AA, Ibrahim MM, Shehata AI, El-Gaaly GA, Daoud M, Fouad D, Rizwana H, Moubayed NMS. Ecotoxicity of Ag-nanoparticles on two microalgae, Chlorella vulgaris and Dunaliella tertiolecta. Arch. Biol. Sci. 2013;65(4):1447-1457. DOI: 10.2298/ABS1304447H.
Short text (in English):
(downloads: 58)