ISSN 0869-6632 (Print)
ISSN 2542-1905 (Online)

For citation:

Nikulina M. V. The new approach to calculation of physiological cost of activity: antinociception and normalization of the respiratory pattern of heart rate variability. Izvestiya VUZ. Applied Nonlinear Dynamics, 2024, vol. 32, iss. 5, pp. 625-635. DOI: 10.18500/0869-6632-003118, EDN: EBQJPT

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Language: 
Russian
Heading: 
Nonlinear Dynamics and Neuroscience
Article type: 
Article
UDC: 
612.176:4, 004.021
DOI: 
10.18500/0869-6632-003118
EDN: 
EBQJPT

The new approach to calculation of physiological cost of activity: antinociception and normalization of the respiratory pattern of heart rate variability

Autors: 
Nikulina Marina Valentinovna, Institute of Applied Physics of the Russian Academy of Sciences
Abstract: 

Purpose of this work is to propose an approach to the assessment of allostatic load based on the antinociceptive effect, which appears, obviously, due to changes in the activity of the endogenous opioid system (EOS); to compare the estimates obtained by measuring the pain threshold and calculating the index of respiratory effects on heart rate variability (HRV).

The method of measuring the pain threshold is based on fixing the latent time of the thermonociceptive reaction (LTTR). The respiratory effect is measured by graphically determining the minimum normalized power of the fast HRV component in the range of 0.16...0.67 Hz, corresponding to the frequency of the respiratory pattern.

Results. Based on small-volume experimental data (4 athletes and 4 episodes of physical activity), a quadratic two-factor regression equation was calculated for LTTR, respiratory effects factor and stress. A high correlation was demonstrated between the respiratory effect on HRV and the LTTR for one studied athlete.

Conclusion. Using the example of sports, it is shown that it is possible to track the physiological cost of activities through LTTR. The inconveniences and subjectivity of the LTTR measurement procedure can be circumvented by replacing it with a normalized numerical index that considers the effect of breathing on HRV and the stress index. The proposed approach demonstrates the presence of reference values in the studied group, but requires further specially planned clinical studies.

Key words: 
endogenous opioid system
antinociception
latent time of thermonociceptive reaction
normalization of heart rate variability
analgesia/nociception index
allostatic load
Acknowledgments: 
The work was partially funded by the Ministry of Science and Higher Education of the Russian Federation within the framework of the state assignment of the IPF RAS, the project № FFUF-2024-0029.
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Received: 
30.12.2023
Accepted: 
09.04.2024
Available online: 
09.09.2024
Published: 
30.09.2024
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